Protocols typically run for 4 to 12 weeks, with extension as needed based on clinical response
doi:10.23750/abm.v91i3.10162 McCartney CR, Marshall JC
Consequently, membrane integrity is lost, producing a detergent-like effect, which eventually disintegrates the membrane by forming micelles, followed by bacterial cell death ( 6 Resistance development possibility Another crucial consideration lies in the potential for bacteria to develop resistance to antibiotics
10.4103/jcrt.JCRT_116_18 J
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