Under section 1886(d)(8)(D) of the Act, the Secretary is required to adjust the standardized amounts so as to ensure that aggregate payments under the IPPS after implementation of the provisions of sections 1886(d)(8)(B), 1886(d)(8)(C), and 1886(d)(10) of the Act are equal to the aggregate prospective payments that would have been made absent these provisions
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The formula is: Dose in mg / Concentration in mg/mL = Volume in mL
elegans unc-52(e669su250) mutants, which undergo progressive paralysis due to aggregation of a metastable version of the perlecan orthologue protein UNC-52 (Mackenzie et al, 1978), which are also highly sensitive to glutathione depletion (Guerrero-Gmez et al, 2019)