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High blood sugars can indirectly impact your fertility by affecting your weight, but theyre also directly linked to disrupted ovulation by causing insulin resistance

Cells were collected and washed with PBS once, and cellular fluorescence was determined by flow cytometry and data were collected by BD FACSCanto and analyzed with FlowJo V.10.1 software

M., Fontenelle, L

Communications Biology 2020, 3 (1), 142142

Crucially, the ROS generated during GSH degradation by CHAC1 may also cause further TP53 mutations, creating a vicious self-reinforcing cycle: CHAC1 activity promotes the very TP53 mutations that allow the tumor to exploit CHAC1s harmful effect for growth