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The clinical amylin combination that has been tested is CagriSema (cagrilintide + semaglutide), not tirzepatide

PRP is also not a one-time treatment

Therefore, the development of this vaccine in clinical trials could be more complicated than in in vivo experiment, given the diverse physiological functions of GPNMB in normal cells

John found that exenatide is an analog of human GLP-1RA, with 53% homology to human GLP-1RA

In contrast, DFP treatment significantly decreased Fe 2+ levels in optic nerve tissue, downregulated TFR1 and Iba-1 expression, and inhibited iron deposition, ferroptosis, microglial activation, and astrocyte proliferation, thereby reducing myelin loss and optic nerve damage in MS mice (Rayatpour et al., 2022)