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Consistent with this, AMPK deletion decreases the activation of AKT and promotes M1 macrophage polarization [89]

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Circ Res 93:354363 Shi F, Wang YC, Zhao TZ, Zhang S, Du TY, Yang CB, Li YH, Sun XQ (2012) Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway

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