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Lipid peroxides, if left unchecked, can cause damage to cell membranes

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It has been studied extensively ever since

Milk thistle may also interact with the following medications, though the interactions are less concerning and only require monitoring after ingestion:2 Fosphenytoin-phenytoin Indinavir Losartan Metronidazole Sirolimus Tolbutamide Vitamin K antagonists On the brighter side, most adverse reactions to milk thistle are minor and brief