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At the moment, the most accurate answer is that safety has not been fully established in humans

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Molecular docking The protein structures of p53 (PDB ID: 8E7A) and HDAC7 (PDB ID: 3C0Y) were obtained from the Protein Data Bank ( Ligands and receptor proteins were preprocessed using AutoDock Tools 1.5.6, and molecular docking was performed using AutoDock Vina

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