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Naughton et al., 2020), and also takes into account the possible downstream mechanisms such as cuproenzyme dysfunction which we believe is highly important to include for a more complete picture of AD

One possible role of a low bilirubin concentration is that of a risk factor for the development of certain diseases

First, the study was conducted on animal models, which may not fully replicate the complexity of human cognitive processes and aging

Beyond brain imaging, attention has increasingly shifted toward peripheral tissues, where accessible biopsies such as skin samples provide a minimally invasive avenue to detect hallmark proteinopathies and extend biomarker discovery beyond the CNS