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Sirtuins NAD + -dependent protein deacylases that consume NAD + to remove post-translational acyl modifications from proteins

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Studies utilizing genetic knockdowns or pharmacological inhibitors have shown that disruption of one antioxidant system often leads to compensatory upregulation and increased reliance on the other, underscoring their functional interdependence [45]

Acknowledgments The authors duly acknowledge the support received from In-charge, Nanaji Deshmukh Plant