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2.2 GABA and Glutamate Regulation Several ASD-linked variants affect GABAergic interneuron development, GABA receptor subunits, or chloride transporters such as SLC12A5 (KCC2)

1, 5, 6, 7 Each successive regimen achieves a less durable response, suggesting emergence of a resistant phenotype and therefore MM remains largely incurable

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A single injection is the primary protocol, with a repeat at 6 weeks if needed