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In line with the hypothesis that CRSR produces an effect on the ECM, another independent study reported a reduced expression of fibroblast activation protein, which is a collagen component of the ECM and TGF-b ( Future Prospect At present, although conventional pharmacological agents used for uterine fibroid continue to exhibit numerous drawbacks, it is still regarded as the ultimate choice of treatment for patients who prefer a noninvasive approach

Reactive oxygen species (ROS) may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered nitric oxide (NO) bioavailability or signaling

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