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Pathway analysis Pathway enrichment analysis comparing cases versus controls for Deoxynivalenol (DON) impact polar metabolites was performed using the MetaboAnalyst 5.0 web platform with the Functional Analysis (MS Peaks) module [49]

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141 The extent to which this allosteric activation model characterizes other metal-sensing MarR proteins yet to be characterized is unknown

The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity