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Many chemical reactions take place in the mitochondria, involving hundreds of substances, enzymes, and ions

In these tissues, iron is also present in iron-sulfur (Fe-S) clusters, and it serves as a cofactor to support ETC, respiration, and oxygen transport (reviewed in Rouault, 2012)

Disruption of circadian rhythms through exposure to LAN appears to trigger a cascade of biological effects, ranging from melatonin suppression and oxidative stress to immune dysregulation, telomere shortening, and epigenetic alterations