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GLP-1 is a natural hormone made in your gut after you eat

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In the present study, we examined changes in glucose metabolism in a mouse systemically harboring a loss of function mutation in Insr (a single amino acid substitution from proline to leucine at 1195 amino acid residue (P1195L)), which has been shown to act as a dominant-negative mutant in heterozygosity 6

At the same time, it inhibits lipogenesis, the process by which your body creates and stores new fat

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