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Animals and housing Following laboratory animal welfare (3Rs: Replacement, Reduction, and Refinement) best practice [31], we acquired 13 adult female mice (C57BL/6 background) from another lab which were excess to experimental requirements, experimentally nave, and slated for euthanasia

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Plasma lipid profiles improved significantly, with total cholesterol levels decreasing by approximately 30% in treated animals

Analysis of GBD 2023 data revealed a pronounced increase in ASPRs, rising from 0.27 per 100,000 males and 0.18 females at ages 2024 years to 3006.4 and 2102.8 in those aged 95 years and above [35, 38]

ADH and ALDH isozyme activity also influences the prevalence of alcohol-induced tissue damage