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The authors demonstrated that of the 25 DEGs investigated, 8 genes (testicular haploid expressed gene ( THEG ), spermatogenesis associated 20 ( SPATA20 ), rhophilin associated tail protein 1 like ( ROPN1L ), glutathione S-transferase F1 ( GSTF1 ), serine kinase 1B ( TSSK1B ), calcium binding protein, spermatid associated 1 ( CABS1 ), adenosine deaminase domain containing 1 ( ADAD1 ), and RIMS binding protein 3 ( RIMBP3 )) are involved in the spermatogenic process or in specific phases of spermatogenesis, and hypothesized that the alteration in the expression of these genes leads to impaired spermatogenesis and, therefore, to male infertility

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Response patterns vary by longevity goal: sleep and circadian rhythm respond on different curves than recovery rhythm, post-stress aging, or cellular aging markers