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CLOCK is involved in obesity-induced disordered fibrinolysis in ob/ob mice by regulating PAI-1 gene expression

Blood pressure reactivity to stress (cold pressor test) was significantly attenuated in the combination group compared to both placebo and L-citrulline alone

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Subsequently, the Myocytes were cultured at either 28C or 37C for an additional 6 hours, serving as the negative control group (28C + 0 M AX, CON) and the thermal stress group, respectively

Initial column temperature was 90 C held for 1.5 min, increased to 220 C at a rate of 20 C min 1 , followed by a second ramp to 320 C at a rate of 10 C min 1 and held for 10 min