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Structurally, parenchyma airspaces enlarged, as indicated by an increase in equivalent airspace diameter (\(D_0\)), and the septum thickened with significant deposition of low-density collagen along with an influx of cells

It also facilitates the transmission of hepatitis and herpes viruses, as well as being implicated in the transmission of an estimated 17% of cases of tuberculosis in the Region

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Similarly, a number of retrospective and prospective studies have found that adolescents experience subjective symptoms of withdrawal, such as craving, nervousness, restlessness, irritability, hunger, difficulty concentrating, sadness, and sleep disturbances, after stopping smoking (McNeil et al