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CoQ10 is a powerful antioxidant that protects cells from the damage that free radicals and reactive oxygen species (ROS) cause when they combine with oxygen

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The mechanisms include (i) the upregulation of transferrin receptors which bind with the transferrin binding iron (ferric iron), (ii) the transportation of ferrous iron into cytosol via divalent metal-ion transporter, which joins the labile iron pool, and (iii) the decreased expression of ferroportin, which is associated with the anaplasia of the cancer tissues with the reduction of metastasis-free survival of patients with breast cancers [19]

10.1016/j.dental.2017.07.015 156 YamashitaM.LazarovM.JonesA

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