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Further studies are needed to better elucidate the immunomodulatory mechanisms and ensure the safety of their clinical use

The fermented Jiegeng extract caused increased level of platycodin D, which significantly reduced both the number of coughs and the cough reflex sensitivity, showing evident anti-inflammatory effects, as demonstrated by the variations in the level of TNF-, IL-6, and IL-1 (Lee et al., 2020)