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NIA P01AG021654, P30AG038072, R37AG18381 and the Paul Glenn Foundation for Medical Research to N.B

Carnitine is a substance that occurs naturally in the body, which the body can synthesize from the amino acids L-lysine, L-methionine and L-glycine in the presence of vitamin C, vitamin B6 and iron

The PDCs currently under clinical/preclinical trials are summarized in Table 6

A handful show benefits in specific medical conditionssuch as tesamorelin for visceral fat accumulation in HIV and GLP-1s in type 2 diabetes, obesity, and heart diseasebut extrapolating these findings to general anti-aging applications lacks scientific support