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The frequency and duration of these injections can vary, with an initial phase involving more frequent administration which is then tailored to the individuals needs based on the improvement of symptoms and B12 levels

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AD patients also display additional biomarkers including cerebrovascular pathology and vascular dysfunctions, decreases in cerebral blood flow, cerebrovascular reactivity, and neurovascular coupling, leading to brain deficits in oxygen and nutrient delivery [4,5]