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In addition, we will discuss the advantages of combining ITC and Se to benefit from their complementary mechanisms of action to potentially prevent the accumulation of alterations during neoplastic transformation that lead to uncontrolled cell growth and loss of genomic stability

Actin was used as an internal reference gene

The anticancer properties of Spirulina also result from its antioxidant and antimutagenic activities (Maddiboyina et al

Glutathione works by regulating melanin production, helping reduce pigmentation and dullness while restoring natural radiance

Naunyn Schmiedebergs Arch Pharmacol 391:12471255 Shalkami A-GS, Hassanein EH, Sayed AM, Mohamed WR, Khalaf MM, Hemeida RA (2021) Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence