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He still smokes cigarettes, and he vapes now, too

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104, 105 TLR2 recognizes not only peptidoglycans from Gram-positive bacteria and bacterial lipopeptides, but also endogenous danger signals, such as 70-kDa heat-shock protein (the latter is known to be released in smoke-exposed airways 104 )

Whether the significant, but rather subtle reduction in the acyl chain length observed in the skin of smokers in this study could affect the overall barrier function remains unclear

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