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Sun HJ, et al

In this context, it has been demonstrated that the restoration of -cell mass can occur not only through proliferation of existing -cells but also via transdifferentiation of other pancreatic cell types, such as -, -, PP-, and ductal epithelial cells (Figure 1B)

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233 Colanic acid (capsular isopolysaccharide acid), a common gut bacterial metabolite extracted from five bacterial mutants, has been confirmed to extend the lifespan of nematodes and Drosophila by regulating ER stress and mitochondrial dynamics in host cells