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In summary, metformin may affect EC through the modulation of glycolysis, lipogenesis, and protein synthesis, as well as inhibition of tumor cell growth and proliferation, and promotion of apoptosis

Accutane (Isotretinoin) is a powerful retinoid medication prescribed for severe, persistent acne that hasnt responded to other treatments

Furthermore, gene expression differences between pre-treatment and post-treatment or resistant and sensitive cell populations can be established to screen for differentially expressed genes (DEGs)