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In mice, a total of 24 selenoproteins have been characterized 46 and targeted deletion of some of these selenoproteins demonstrated their essential roles in developmental processes and in disease pathogenesis

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These findings open the opportunities for therapy targeting metabolic cross talk between cancer cells and cancer-associated fibroblasts [159]

[DOI] [PubMed] [Google Scholar] 89.Simmonds M.J., Detterich J.A., Connes P

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