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In order to keep the Principal Investigator and participant blind to the medication condition, medication and placebo pills were administered by staff who were not otherwise in contact with the participants

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Schneider A, Lhr JM, Singer MV

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In addition, as marijuana smoking is usually associated with deeper inhalation, longer breath-holding times, use of unfiltered marijuana cigarettes (joints) with a potential for greater delivery of tar to the lungs [47], and the marijuana smoke being even more cytotoxic and mutagenic [48, 49] in comparison with tobacco smoking