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Peyronie's disease: Some studies have shown that men who took ALC daily for 3 months had less pain and curving of the penis

81,85,86 Matricaria recutita (German chamomile) is another popular herb with spasmolytic, anti-inflammatory, and mild sedative properties

Statements Author contributions MK, MZ, and JA contributed equally to the writing of the manuscript

This creates maladaptive epigenetic memory , meaning the body remembers prior heat stress and maintains altered metabolic and inflammatory responses even after the exposure ends

Some studies also investigate DSIP indirectly in pain and chronic pain models, primarily by evaluating how sleep quality and stress modulation affect pain perception rather than through direct analgesic effects