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There are several ways in which smoking causes pelvic floor dysfunction, some of which include the following: Reduced Blood Flow: Nicotine and other chemicals restrict blood circulation, limiting oxygen and nutrients to pelvic tissues, which can weaken muscle tone

The disease activity index (DAI) was calculated as a composite score on the basis of relative body weight loss, changes in the colon length/weight ratio, and the presence of occult blood in stool samples

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, Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines , Oral Oncology , vol