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1c,d, and Supplementary Table 2) Characterizing four senolytic chloroacetamides Among the electrophilic compounds with senolytic activity identified, we concentrated on four senolytic chloroacetamides (SCLAs

FOXO4-DRI is a D-retro-inverso peptide built from a FOXO4 fragment that binds p53, joined to a cell-penetrating sequence, with a molecular weight near 4.8 kDa

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These two structures do not have the ability to bind covalently to proteins and correspondingly, as demonstrated in skin test and basophil activation test, cannot be recognized by sIgE from allergic patients 20

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