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LDHB has been shown to be essential for KRAS -mutant lung cancer progression [2527] and to regulate stem cell properties and mitochondrial functions [28]

Neural Regen Res 16(9):1730 Ramsaransing GS, Fokkema MR, Teelken A, Arutjunyan AV, Koch M, De Keyser J (2006) Plasma homocysteine levels in multiple sclerosis

The dramatic report by the WHO has shown that by 2050, drug resistance could catch up to cancer and sufficiently damage the economy if actions are not taken ( Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and others that have become resistant to one or multiple types of antibiotics, contributing to the dramatic situation in healthcare (Figure 2)

Excess Heme Upregulates Heme Oxygenase 1 and Promotes Cardiac Ferroptosis in Mice with Sickle Cell Disease