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One small retrospective case series investigated intra-articular BPC-157 injections for knee pain but lacked rigorous methodology, control groups, and long-term follow-up ([6])

In parallel, metformin suppresses apoptosis by reducing the Bax/Bcl-2 ratio and caspase-3 activation (Van et al., 2023

Toxicol., 2001, doi: 10.1002/jat.796

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Although the paper states that 49 started the second phase of the study and therefore, according to the protocol, had a second glutathione measurement, pre- and post-intervention erythrocyte glutathione is only provided for 38 participants with no comparison between the two arms of the study with levels being compared to an adult reference range provided by the laboratory