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More than half of morbidity cost is estimated to be caused by musculoskeletal disorders in the case of active smoking and by diabetes in the case of SHS

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Thyroid hormones : Smoking can influence thyroid function by increasing autoimmune activity or altering hormone metabolism, decreasing thyroid-stimulating hormone or TSH levels and potentially increasing the production of T3 while reducing T4 levels

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Modeling data from recent research shows that between 1980 and 2018, menthol cigarettes were responsible for 10.1 million extra smokers and 378,000 early deaths