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Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

Factors such as individual health profile, treatment response, and tolerance levels influence the treatment plan

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The RMSF for Tyr-72, Asp-74, Trp-86, Gly-120, Gly-121, Tyr-124, Tyr-133, Glu-202, Ser-203, Trp-286, Phe-295, Phe-297, Tyr-337, Phe-338, Tyr-341, His-447, and Gly-448 were selected and ranked, resulting in 6 residues being chosen from each of the 9 simulations (Supplementary Table S17)

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