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However, they project that smoking prevalence would drop by an additional 12% if the MLSA were raised to 21, compared to only an additional 3% if the MLSA were raised to 19

doi:10.3233/JCB-230120 Food Chem

The researchers suggest that the nature and impact of the consequences may depend on the substances that the devices contain, including nicotine, solvents and flavorings

Although there is no consensus regarding the increased activation of nicotinamide adenine dinucleotide phosphate oxidase by smoking, xanthine oxidase, an ROS-producing system, is activated by smoking