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Specifically, women have greater craving during acute nicotine withdrawal and more difficulty quitting than men, but men experience greater nicotine-induced reinforcement/reward 59
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(A Juul team is now exploring the market in Central and Western Europe, and an Asia team is in the works.) Last year, Juul added a small gray bar to its packaging that reads The alternative for adult smokers. The company had considered a bigger, more aggressive statement, but executives were afraid that it would make the product seem edgy, like a parental-advisory warning on a CD cover
Therefore, we speculate that CS can activate more eosinophils in the airway to recruit more eosinophils and aggravate airway remodeling