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Upon asking the participants to estimate the severity of withdrawal symptoms during fasting time using a score of severity (05, weak-sever) (Table 4), more than half (n = 288, 53%) of the e-cig users reported that the severity of withdrawal symptoms ranged between weak (score of 1, 20.1%) to very severe (score of 5, 0.8%)

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The strength relies on the first systematized utilization of GBD 2019 data and methods to estimate the global burden of disease and its trends for lip and oral cavity cancer attributable to smoking by sex, age, and SDI