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5c and d)
A 100mg vial provides approximately 33 administrations , lasting about 67 weeks when administered 5 days per week
Studies have found that berberine can effectively alleviate the motor dysfunction of HTT mice and prolong their survival time, further studies proves that berberine promote the degradation of mutant HTT protein through enhancing autophagy function, thereby reducing the accumulation of mutant huntingtin protein (Jiang et al., 2015b)
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