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Future studies should prioritize defining the precise abundance threshold of Akkermansia muciniphila that balances its beneficial and deleterious effects on the intestinal barrier, investigating the molecular mediators (e.g., specific metabolites or surface proteins) that underpin its dual regulatory role, and developing targeted interventions (e.g., precision probiotics or microbiota modulators) to sustain its homeostatic levelswith the goal of ultimately mitigating OA progression via the gut-joint axis

Furthermore, the presence of gastrointestinal symptoms during acute COVID-19 infection has been identified as an independent risk factor for developing post-COVID FGIDs

Most adults tolerate them well

Find out the best way to take curcumin and turmeric supplements to increase absorption and bioavailability, plus the best way to cook with turmeric spice