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Side effects, although uncommon, include diarrhea, headache, itching, and nausea

has come up with an inverse relationship between body mass index (BMI) and testosterone, testosterone to estradiol, ejaculate volume, sperm concentration and morphology

In particular, when discussing how tobacco affected the stomach, it mentioned the link between excessive smoking and weight loss, stating: Nicotine has yet another action on the stomach: it restrains those automatic contractions of the stomach muscle which translated themselves into consciousness as the sensation of hunger

But Rees also said they need to be interpreted in the context of the global fight against tobacco