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Allergic dermatitis was associated with active (pooled RR, 1.36 [95% CI 1.171.46]) and passive smoking (pooled RR, 1.06 [95% CI 1.011.11])

Furthermore, the study found that cannabidiol exposure causes an induction in immunosuppressive T regulatory cells and a reduction in interleukin 2 (IL-2), leading to disruption of T cell functions and suppression of adaptive immune responses in the lungs of exposed mice

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People who smoke only 4 or fewer cigarettes a day can experience the negative effects of smoking and they still have a greater risk of premature death than nonsmokers