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In this case, the use of antioxidant supplements such as creatine can have positive effects on the antioxidant system

10.1111/j.1524-475X.2008.00440.x 107 RussellJ

Kaur H, Ganguli D, Bachhawat AK (2012) Glutathione degradation by the alternative pathway (DUG pathway) in Saccharomyces cerevisiae is initiated by (Dug2p-Dug3p)2 complex, a novel glutamine amidotransferase (GATase) enzyme acting on glutathione

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Using mice to examine p53 functions in cancer, aging, and longevity