As one of several starting compounds of glutathione, glycines importance becomes even more highlighted
Moreover, its ability to modulate immune responses, promote angiogenesis, anti inflammatory and enhance tissue repair mechanisms underscores its multifaceted therapeutic potential, making it a subject of interest for further investigation in various medical applications including gut health
O -glycosides (e.g., isoquercitrin) are typically hydrolyzed in the upper gastrointestinal tract to release aglycones like quercetin, while C -glycosides (e.g., orientin, vitexin), due to their structural stability, are only metabolized into absorbable forms in the colon by gut microbiota (Xie et al., 2022)
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Furthermore, functional pathways associated with flavonoid biosynthesis and antigen processing and presentation were enhanced, while metabolic pathways related to tyrosine and other compounds were reduced