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GABAergic dysfunction in mood disorders

10.1016/j.ebiom.2023.104527 47

Graphical abstract Similar content being viewed by others Background Nephropathic cystinosis is a rare, autosomal recessive lysosomal storage disease with an incidence of 1:100,000 to 1:200,000 live births [1]

Primary Research Areas NNMT enzymology and pharmacology the lead first-in-class selective small-molecule NNMT inhibitor used to validate the entire target class [1,2]

The potential neurological benefits of BPC-157 are nerve fiber regeneration, dopaminergic pathway modulation, neuroprotection from oxidative stress, and improved behavioral outcomes following brain injury