do cigarettes control inflammatory bowel Smoking may cause disease Frontiers | Impact of Cigarette

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(2) The expansion follows a systematic corridor strategy, extending along major interstates: I-10 eastward through the Gulf Coast, I-95 northward up the Atlantic seaboard, I-75 and I-65 through the Southeast, I-25 and I-70 into Colorado and the Mountain West, and I-40 westward

Morris Coats, A Note on Estimating Cross-Border Effects of State Cigarette Taxes, National Tax Journal 48:4 (December 1995): 573-584, ntj-v48n04p573-84-note-estimating-cross-border.pdf?v=%CE%B1&r=35923133871196367

In the case of men, in addition to affecting seminal quality, smoking could be related to alterations in spermatogenesis, to greater fragmentation of sperm DNA and even to problems of erectile dysfunction

Edward formalized what had been the practice off and on for several decades at that point