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E-Liquid : 20mg nicotine salt, auto-refill system

In 1900, Arents obtained a patent for a machine that manufactured cigars, an invention that led to the formation of the American Machine and Foundry Company, now called AMF, and a subsidiary known as International Cigar Machinery Company

75 See Section 10.6.7 Filter innovation for more information

However, a research constraint with assessing the impact of e-cigarettes is that most vapers were formerly smokers, or are dual-users of ENDS and tobacco, making it difficult to isolate the impact of ENDS

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