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[25] In addition, the immune system starts to recover in 15 days as the inhibitory effects of cigarettes on macrophages are removed

This biopsy-based approach -- using sophisticated single-cell analyses in collaboration with Sandeep Datta, M.D., Ph.D., at Harvard University -- revealed widespread infiltration of T-cells engaged in an inflammatory response in the olfactory epithelium, the tissue in the nose where smell nerve cells are located

Additional Resources CDCs page on Heated Tobacco Products Public Health Law Centers Heated Cigarette Regulations 50 State Review and factsheet Heated Cigarettes: How States Can Avoid Getting Burned Global Marketing of IQOS: The Philip Morris Campaign to Popularize Heat Not Burn Tobacco, Stanford Research into the Impact of Tobacco Advertising WHOs Heated tobacco products: a brief (2020) and Heated Tobacco Products Information Sheet (2 nd edition) Campaign for Tobacco Free Kids Heated Tobacco Products UCSF Smoking Cessation Leadership Centers recorded webinar: Unboxing iQOS: History, risk perceptions, and clinical implications Understanding Heated Tobacco Products: Current Issues and Recent Findings (April 2025), STOP

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