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A 2022 Cochrane review, which is considered the gold standard for the assessment of research into the efficacy and safety of safer nicotine products, has stated that There was moderatecertainty evidence that heated tobacco users have lower exposure to toxicants/carcinogens than cigarette smokers

Lets consider one of the major neurotransmitters in the brain called Acetylcholine

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They are now measuring the participants lung function to understand how exposure to tobacco smoke influences their respiratory health in the longer term

How does nicotine affect the body