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AZM not only activates the proteasome but also boosts NOX4 degradation by specifically enhancing its ubiquitination via STUB1, which is crucial for mitigating TGF--mediated myofibroblast differentiation by regulating reactive oxygen species (ROS)

Understanding the epigenetic consequences of tobacco exposure has not only deepened insight into disease etiology but also opened new avenues for prevention and intervention

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